How Startup Theranos Has Struggled With Its Blood-Test Technology

John Carreyrou, How Startup Theranos Has Struggled With Its Blood-Test Technology. The Wall Street Journal, 16 October 2015. “On Theranos Inc.’s website, company founder Elizabeth Holmes holds up a tiny vial to show how the startup’s “breakthrough advancements have made it possible to quickly process the full range of laboratory tests from a few drops of blood.” The company offers more than 240 tests, ranging from cholesterol to cancer. It claims its technology can work with just a finger prick. Investors have poured more than $400 million into Theranos, valuing it at $9 billion and her majority stake at more than half that. The 31-year-old Ms. Holmes’s bold talk and black turtlenecks draw comparisons to Apple Inc. cofounder Steve Jobs. But Theranos has struggled behind the scenes to turn the excitement over its technology into reality. At the end of 2014, the lab instrument developed as the linchpin of its strategy handled just a small fraction of the tests then sold to consumers, according to four former employees.”

Winner of the 2015 George Polk Award for Financial Reporting. “The award for Financial Reporting will go to John Carreyrou of The Wall Street Journal whose investigation of Theranos, Inc. raised serious doubts about claims by the firm and its celebrated 31-year-old founder, Elizabeth Holmes, that its new procedure for drawing and testing blood was a transformational medical breakthrough in wide use at the firm’s labs. Carreyrou’s well-researched stories, reported in the face of threats of lawsuits and efforts to pressure some sources to back off of their accounts, led to a reevaluation of Theranos’ prospects among investors and have been followed by regulatory actions against the company and widespread discussion that publications and institutions from Fortune and The New Yorker to Harvard and the White House may have been too quick to hail Holmes, a Stanford dropout whose personal wealth at the height of her startup’s rise was an estimated $4.5 billion, as a success story in the tradition of Steve Jobs, Bill Gates and Mark Zuckerberg.”

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The Black Family in the Age of Mass Incarceration

Ta-Nehisi Coates, The Black Family in the Age of Mass Incarceration. The Atlantic, October 2015. “American politicians are now eager to disown a failed criminal-justice system that’s left the U.S. with the largest incarcerated population in the world. But they’ve failed to reckon with history. Fifty years after Daniel Patrick Moynihan’s report ‘The Negro Family’ tragically helped create this system, it’s time to reclaim his original intent.”

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The Miracle Industry: America’s Most Admired Lawbreaker, Johnson & Johnson

Steven Brill, The Miracle Industry: America’s Most Admired Lawbreaker, Johnson & Johnson. The Huffington Post Highline, 15 September 2015. Chapter I of 15, “The Credo Company. Backstage at Johnson & Johnson.” “The Johnson & Johnson Risperdal story is a complex, roller coaster tale. The details count. They are important in understanding the people and impulses behind the drugs we take. To tell that story in a way that is digestible but complete, The Huffington Post Highline and I are trying something new: a DocuSerial. It’s a reconstruction of an old story-telling genre that allows us to deploy the modern tools of digital communication to engage readers in old-fashioned, long-form feature journalism.

Every day for the next 15 days, a new chapter of the Johnson & Johnson story will be posted here. Along with the text, we will post not only a rich array of photos and graphics, but also links to every document—court transcripts, internal emails, FDA staff memos—referred to in that day’s chapter. That way, you will be able to delve more deeply into the materials that are quoted. (You’ll also be able to make sure I held true to the context of the material I quote.)”

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Outside Psychologists Shielded U.S. Torture Program, Report Finds

James Risen, Outside Psychologists Shielded U.S. Torture Program, Report Finds. The New York Times, 10 July 2015. “A 542-page report [the result of a seven-month investigation by a team led by David Hoffman, a Chicago lawyer with the firm Sidley Austin at the request of the American Psychological Association’s board] concludes that prominent psychologists worked closely with the C.I.A. to blunt dissent inside the agency over an interrogation program that is now known to have included torture. It also finds that officials at the American Psychological Association colluded with the Pentagon to make sure the association’s ethics policies did not hinder the ability of psychologists to be involved in the interrogation program.”

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Secret World War II Chemical Experiments Tested Troops By Race

Caitlin Dickerson, Secret World War II Chemical Experiments Tested Troops By Race. NPR, 22 June 2015. Part 1 of a two-part investigation on mustard gas testing conducted by the U.S. military during World War II. “As a young U.S. Army soldier during World War II, Rollins Edwards knew better than to refuse an assignment. When officers led him and a dozen others into a wooden gas chamber and locked the door, he didn’t complain. None of them did. Then, a mixture of mustard gas and a similar agent called lewisite was piped inside. “It felt like you were on fire,” recalls Edwards, now 93 years old. “Guys started screaming and hollering and trying to break out. And then some of the guys fainted. And finally they opened the door and let us out, and the guys were just, they were in bad shape.”

Edwards was one of 60,000 enlisted men enrolled in a once-secret government program — formally declassified in 1993 — to test mustard gas and other chemical agents on American troops. But there was a specific reason he was chosen: Edwards is African-American. “They said we were being tested to see what effect these gases would have on black skins,” Edwards says. An NPR investigation has found evidence that Edwards’ experience was not unique. While the Pentagon admitted decades ago that it used American troops as test subjects in experiments with mustard gas, until now, officials have never spoken about the tests that grouped subjects by race. For the first time, NPR tracked down some of the men used in the race-based experiments. And it wasn’t just African-Americans. Japanese-Americans were used as test subjects, serving as proxies for the enemy so scientists could explore how mustard gas and other chemicals might affect Japanese troops. Puerto Rican soldiers were also singled out.”

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How the Red Cross Raised Half a Billion Dollars for Haiti and Built Six Homes

Justin Elliott, ProPublica, and Laura Sullivan, NPR, How the Red Cross Raised Half a Billion Dollars for Haiti and Built Six Homes. ProPublica and NPR, 3 June 2015. “In late 2011, the Red Cross launched a multimillion-dollar project to transform the desperately poor area, which was hit hard by the earthquake that struck Haiti the year before. The main focus of the project — called LAMIKA, an acronym in Creole for “A Better Life in My Neighborhood” — was building hundreds of permanent homes. Today, not one home has been built in Campeche. Many residents live in shacks made of rusty sheet metal, without access to drinkable water, electricity or basic sanitation. When it rains, their homes flood and residents bail out mud and water. The Red Cross received an outpouring of donations after the quake, nearly half a billion dollars. The group has publicly celebrated its work. But in fact, the Red Cross has repeatedly failed on the ground in Haiti. Confidential memos, emails from worried top officers, and accounts of a dozen frustrated and disappointed insiders show the charity has broken promises, squandered donations, and made dubious claims of success. The Red Cross says it has provided homes to more than 130,000 people. But the actual number of permanent homes the group has built in all of Haiti: six.”

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Truth and Reconciliation Commission of Canada, Honoring the Truth, Reconciling for the Future

Honoring the Truth, Reconciling for the Future, Truth and Reconciliation Commission of Canada. Summary of the Final Report of the Truth and Reconciliation Commission of Canada. 31 May 2015. “For over a century, the central goals of Canada’s Aboriginal policy were to eliminate Aboriginal governments; ignore Aboriginal rights; terminate the Treaties; and, through a process of assimilation, cause Aboriginal peoples to cease to exist as distinct legal, social, cultural, religious, and racial entities in Canada. The establishment and operation of residential schools were a central element of this policy, which can best be described as ‘cultural genocide.'”

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A Choice for Recovering Addicts: Relapse or Homelessness

Kim Barker, A Choice for Recovering Addicts: Relapse or Homelessness. The New York Times, 30 May 2015. “After a lifetime of abusing drugs, Horace Bush decided at age 62 that getting clean had become a matter of life or death. So Mr. Bush, a homeless man who still tucked in his T-shirts and ironed his jeans, moved to a flophouse in Brooklyn that was supposed to help people like him, cramming into a bedroom the size of a parking space with three other men.

Mr. Bush signed up for a drug-treatment program and emerged nine months later determined to stay sober. But the man who ran the house, Yury Baumblit, a longtime hustler and two-time felon, had other ideas.

Mr. Baumblit got kickbacks on the Medicaid fees paid to the outpatient treatment programs that he forced all his tenants to attend, residents and former employees said. So he gave Mr. Bush a choice: If he wanted to stay, he would have to relapse and enroll in another program. Otherwise, his bed would be given away.”

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You Call This A Medical Emergency? Death and Neglect at Rikers Island Women’s Jail

Erika Eichelberger, You Call This a Medical Emergency? Death and Neglect at Rikers Island Women’s Jail. The Intercept, 29 May 2015.  On the second day Jackie Caquias was “at the Rose M. Singer Center, [Rikers Island’s] only women’s facility, the medical clinic ran lab tests that showed Jackie’s liver was severely stressed. Blood work two weeks later showed the same. Yet the doctors at Rikers didn’t send Jackie to a gastroenterologist for a liver exam. Instead, they prescribed her Tylenol 3 and iron, both dangerous for people with liver problems. The Tylenol 3 was discontinued after a week, but even after medical staff ordered the iron be stopped, the pharmacy continued dispensing it. Less than a month after Jackie arrived at Rose M. Singer, her system began to fail. She grew disoriented and delusional, and began vomiting so severely that blood and bodily tissue came up — all signs of acute liver failure. On June 25, 2014, after spending weeks in Elmhurst Hospital comatose and hooked up to machines, Jackie died.”

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The Price of Nice Nails: Manicurists are routinely underpaid and exploited

Sarah Maslin Nir, The Price of Nice Nails: Manicurists are routinely underpaid and exploited, and endure ethnic bias and other abuse. The New York Times, 7 May 2015. “UNVARNISHED: Articles in this [two-part] series [examine] the working conditions and potential health risks endured by nail salon workers.”

Update from the Public Editor of The New York Times: Margaret Sullivan, New Questions on Nail Salon Investigation, and a Times Response, The New York Times, 6 November 2015. “My take: The series and its author, Sarah Maslin Nir, had admirable intentions in speaking for underpaid or abused workers. And the investigation did reveal some practices in need of reform. But, in places, the two-part investigation went too far in generalizing about an entire industry. Its findings, and the language used to express them, should have been dialed back — in some instances substantially…. There is a legitimate and important subject here about low-paid work done by immigrants in New York City — not just in nail salons. It includes, for example, the food-delivery business and many other services that affluent New Yorkers take for granted. I’m always glad to see The Times take on situations in which the poor and voiceless are exploited. But, in doing so, it must protect its reputation for accuracy and rigor above all. My recommendation is that The Times write further follow-up stories, including some that re-examine its original findings and that take on the criticism from salon owners and others — not defensively but with an open mind.”

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